Barrymore’s career began when she was auditioned for a dog food commercial when she was 11 months old. When she was bitten by her canine co-star, the producers were afraid she would cry, but she merely laughed, and was hired for the job.
She made her feature film debut inAltered States (1980), in which she had a small part. A year later, she played Gertie, the younger sister of Elliott, in E.T. the Extra-Terrestrial, which made her one of the most famous child stars of the time and earned her the Young Artist Award as Best Young Supporting Actress in a Motion Picture in 1982.